A handshake is a common greeting or gesture of agreement between two people. It typically involves grasping each other's right hand and shaking it up and down. Handshakes are often used in formal settings, such as business meetings, to convey respect and establish rapport. In many cultures, a handshake signifies trust and goodwill. The way a handshake is performed can convey different meanings; for example, a firm handshake may indicate confidence, while a weak handshake might suggest uncertainty. Handshakes are also often accompanied by eye contact and a smile to enhance the friendly nature of the interaction.