HTLV-I-associated Myelopathy (HAM) is a neurological condition caused by the Human T-lymphotropic virus type I (HTLV-I). This virus primarily affects the spinal cord, leading to symptoms such as weakness, stiffness, and pain in the legs. It can also cause difficulties with walking and bladder control. The condition is a progressive disorder, meaning symptoms can worsen over time. Diagnosis typically involves clinical evaluation, imaging studies, and blood tests to detect the presence of HTLV-I. While there is no cure, treatments focus on managing symptoms and improving the quality of life for affected individuals.