Gregory House is a fictional character from the television series House, M.D., which aired from 2004 to 2012. He is portrayed by actor Hugh Laurie and is known for his brilliant diagnostic skills as a medical doctor specializing in infectious diseases and nephrology. House is often depicted as a misanthropic and unconventional physician who relies on his keen intellect and unorthodox methods to solve complex medical cases. The character is also recognized for his struggles with chronic pain and addiction to pain medication, which influence his personality and relationships with colleagues. House leads a team of doctors at Princeton-Plainsboro Teaching Hospital in New Jersey, where he frequently clashes with hospital administration and his boss, Lisa Cuddy.