Granulomatous diseases are a group of conditions characterized by the formation of granulomas, which are small clusters of immune cells that form in response to chronic inflammation. These granulomas can develop in various tissues and organs, often as a reaction to infections, foreign substances, or autoimmune processes. Common examples include sarcoidosis, tuberculosis, and Crohn's disease. The presence of granulomas can disrupt normal tissue function and lead to symptoms depending on the affected area. Diagnosis typically involves imaging studies, biopsies, and laboratory tests to identify the underlying cause. Treatment may vary, focusing on managing symptoms and addressing the root cause of the inflammation.