GABA_A Receptor
The GABA_A receptor is a type of neurotransmitter receptor in the brain that responds to the neurotransmitter gamma-aminobutyric acid (GABA). It plays a crucial role in inhibiting neuronal activity, helping to regulate mood, anxiety, and overall brain function. When GABA binds to the receptor, it typically causes the opening of ion channels, allowing negatively charged ions to enter the neuron, which makes it less likely to fire.
These receptors are important targets for various medications, including benzodiazepines and barbiturates, which enhance the effects of GABA. Dysregulation of GABA_A receptors is associated with several neurological and psychiatric disorders, highlighting their significance in maintaining mental health.