The Food, Drug, and Cosmetic Act (FDCA) is a U.S. law enacted in 1938 to ensure the safety and efficacy of food, drugs, and cosmetics. It established the framework for the regulation of these products, requiring manufacturers to provide evidence of safety before they can be marketed. The act also created the Food and Drug Administration (FDA), which oversees compliance and enforcement. The FDCA has undergone several amendments to address emerging health concerns and technological advancements. It covers a wide range of products, including prescription medications, over-the-counter drugs, and cosmetics, ensuring that they meet safety standards to protect public health.