The First Metacarpal is one of the five long bones in the hand, specifically located in the palm. It connects the wrist to the thumb, playing a crucial role in thumb movement and grip. This bone is shorter and thicker than the other metacarpals, providing stability and strength for the thumb's various functions. Anatomically, the First Metacarpal articulates with the wrist bones, known as the carpals, and the proximal phalanx of the thumb. Its unique structure allows for a wide range of motion, essential for tasks such as grasping and pinching. The health of the First Metacarpal is vital for overall hand function.