A Febrile Non-Hemolytic Reaction is a common response that can occur after a blood transfusion. It usually happens when the recipient's immune system reacts to white blood cells or other components in the donated blood. Symptoms often include fever, chills, and discomfort, but the reaction is generally mild and resolves on its own without serious complications. To manage this reaction, healthcare providers may give medications like acetaminophen to reduce fever and discomfort. It's important for patients to report any symptoms they experience during or after a transfusion, as this helps ensure their safety and improve future transfusion practices.