Factors Vb is a protein that plays a crucial role in the blood coagulation process. It is part of the coagulation cascade, which is a series of events that lead to the formation of a blood clot. When a blood vessel is injured, Factors Vb helps convert prothrombin into thrombin, an essential step in clot formation. This protein is produced in the liver and is activated by the presence of Factor Xa. Deficiencies or abnormalities in Factors Vb can lead to bleeding disorders, making it important for maintaining proper blood clotting and overall vascular health.