Factor VIII is a crucial protein in the blood clotting process, primarily involved in the formation of blood clots. It works by helping platelets stick together and form a stable clot, which is essential for stopping bleeding. Deficiency or dysfunction of Factor VIII can lead to bleeding disorders, the most common being Hemophilia A. Factor VIII is produced in the liver and circulates in the bloodstream in an inactive form. When a blood vessel is injured, it is activated and interacts with other clotting factors, particularly Factor IX, to initiate the clotting cascade. This process is vital for wound healing and maintaining hemostasis.