Expedition 16 was a mission to the International Space Station (ISS) that took place from October 2007 to April 2008. It was part of the NASA program and involved a crew of six astronauts, including Peggy Whitson, who served as the commander. The mission focused on scientific research and technology demonstrations in microgravity. During Expedition 16, the crew conducted various experiments in fields such as biology, physics, and materials science. They also performed maintenance tasks on the ISS and prepared for future missions. The successful completion of this expedition contributed to the ongoing development of the ISS and its research capabilities.