Eclipse Phase is a science fiction role-playing game set in a post-apocalyptic future where humanity has developed advanced technologies, including mind uploading and genetic engineering. Players take on the roles of transhuman characters who navigate a world filled with political intrigue, existential threats, and the remnants of a collapsed civilization. The game emphasizes themes of identity, survival, and the consequences of technological advancement. Players can explore various factions, such as the Titanian Commonwealth or Fallen London, and engage in missions that challenge their morals and beliefs while uncovering the mysteries of the universe and their own existence.