E49 is a designation that can refer to various things depending on the context. In the realm of transportation, it may refer to a specific route or highway, such as a European road or a local transit line. It can also denote a model number for vehicles, electronics, or machinery, indicating a particular version or specification. In the context of technology, E49 might refer to a specific code or standard within a software or hardware system. It could also be associated with a product line, such as E49 in the automotive industry, representing a particular feature set or design.