The title "Duke of Alcalá de los Gazules" is a noble title in the Spanish peerage, created in 1860. It is associated with the town of Alcalá de los Gazules in the province of Cádiz. The title has been held by various noble families, contributing to the history and culture of the region. The dukedom is part of a broader system of Spanish nobility, which includes various ranks such as marquess, count, and baron. The current holder of the title is a member of the House of Medinaceli, one of the most prominent noble families in Spain.