The Duke of Anjou is a title historically associated with the region of Anjou in France. It has been held by various noble families, most notably the House of Valois and the House of Bourbon. The title has often been linked to significant political and military events in French history, including the Wars of Religion. One of the most famous Dukes of Anjou was Henry III of France, who was also the last of the Valois kings. The title has also been claimed by various pretenders, including the Duke of Anjou from the Spanish royal family, who is a descendant of the Bourbon line.