Dren is a fictional character from the 2009 science fiction film "Splice," directed by Vincenzo Natali. She is a hybrid creature created by scientists Clive Nicoli and Elsa Kast through genetic engineering, combining human and animal DNA. Dren exhibits unique physical traits and abilities, which lead to complex ethical and emotional dilemmas for her creators. As Dren matures, her behavior becomes increasingly unpredictable, reflecting both her animalistic instincts and human-like emotions. The film explores themes of scientific responsibility, the consequences of playing with nature, and the bond between creator and creation, ultimately raising questions about identity and morality in the realm of genetic manipulation.