Donald J. Cram was an American chemist born on April 22, 1919, in Houghton, Michigan. He is best known for his work in the field of supramolecular chemistry, which focuses on understanding how molecules interact and assemble into larger structures. Cram's research contributed significantly to the development of molecular recognition, a concept that has applications in various scientific fields. In 1987, Cram was awarded the Nobel Prize in Chemistry alongside Jean-Marie Lehn and Donald J. Cram for their contributions to supramolecular chemistry. His innovative work has had a lasting impact on chemistry, influencing areas such as drug design and materials science. Cram passed away on August 17, 2020.