The District of Pčinja is located in southern Serbia, bordered by North Macedonia to the south. It is part of the Southern and Eastern Serbia region and includes several municipalities, with Vranje as its administrative center. The district is known for its diverse landscapes, including hills and valleys, and has a rich cultural heritage. The economy of the District of Pčinja is primarily based on agriculture, with crops such as wheat and corn being significant. Additionally, the area has a history of mining and some light industry. The district is also home to various historical sites and natural attractions, making it a region of interest for both residents and visitors.