Dipeptidyl Peptidase-4 (DPP-4) is an enzyme found in the body that plays a crucial role in glucose metabolism. It helps regulate blood sugar levels by breaking down certain hormones, such as glucagon-like peptide-1 (GLP-1), which are involved in insulin secretion and appetite control. DPP-4 inhibitors are a class of medications used to treat type 2 diabetes. By blocking the action of DPP-4, these drugs increase the levels of GLP-1, leading to improved insulin response and lower blood sugar levels. This makes them an important option for managing diabetes effectively.