The "Destruction of Sodom" refers to the biblical account of the city of Sodom, which, along with Gomorrah, was destroyed by divine judgment. According to the Book of Genesis, the cities were known for their wickedness and immorality. God decided to destroy them due to the outcry against their sinful behavior, but He spared the righteous man Lot and his family. Before the destruction, two angels visited Lot to warn him of the impending doom. They instructed him to flee the city with his family and not look back. As they escaped, fire and brimstone rained down, completely obliterating Sodom and Gomorrah, serving as a cautionary tale about the consequences of sin.