Desha County is located in the southeastern part of Arkansas, bordered by the Arkansas River. It was established in 1836 and is named after Benjamin Desha, a soldier and politician. The county seat is Arkadelphia, which serves as the administrative center. The county is known for its rich agricultural land, primarily producing crops like cotton and soybeans. It also features several natural attractions, including parts of the Delta Heritage Trail State Park, which offers recreational opportunities for residents and visitors alike.