Derek Venturi's Friends are a group of characters from the animated television series Daria. They include Jane Lane, a talented artist with a sarcastic sense of humor, and Trent Lane, Jane's laid-back brother and lead singer of the band Mystik Spiral. Together, they navigate the challenges of high school life and social dynamics. The friends often provide support and comic relief for Derek, who is known for his unique perspective on life. Their interactions highlight themes of friendship, individuality, and the struggles of adolescence, making them relatable to many viewers.