DOPA-Responsive Dystonia
DOPA-Responsive Dystonia is a rare movement disorder characterized by muscle stiffness and abnormal postures, primarily affecting the legs. It typically begins in childhood or adolescence and can lead to difficulty walking. The condition is caused by a deficiency in the enzyme that helps produce dopamine, a neurotransmitter essential for smooth muscle movement.
The disorder is often responsive to treatment with levodopa, a medication that increases dopamine levels in the brain. This response is a key feature that distinguishes it from other types of dystonia. Early diagnosis and treatment can significantly improve mobility and quality of life for those affected.