DMARDs, or Disease-Modifying Anti-Rheumatic Drugs, are medications used to treat autoimmune diseases like rheumatoid arthritis. They work by slowing down the disease's progression and reducing inflammation, which helps prevent joint damage and improves overall quality of life. Unlike pain relievers, DMARDs target the underlying causes of the disease. These drugs can take several weeks to show their full effects, and they may require regular monitoring by a healthcare provider. Common types of DMARDs include methotrexate and sulfasalazine. While they can be very effective, they may also have side effects, so it's important for patients to discuss their options with their doctor.