Cyclin-Dependent Kinases (CDKs) are a family of enzymes that play a crucial role in regulating the cell cycle. They are activated by binding to specific proteins called cyclins, which help control various phases of cell division. CDKs phosphorylate target proteins, leading to changes that drive the cell through its cycle. The activity of CDKs is tightly regulated to ensure proper cell function and division. Dysregulation of CDKs can lead to uncontrolled cell growth, contributing to diseases such as cancer. Understanding CDKs is essential for developing targeted therapies in oncology and other fields of medicine.