The Cuyapaipe Indian Reservation is located in San Diego County, California. It is home to the Cuyapaipe Band of Diegueño Mission Indians, a Native American tribe that is part of the larger Diegueño group. The reservation covers approximately 1,000 acres and is situated in a rural area, providing a natural environment for its residents. Established in the early 20th century, the reservation serves as a cultural and community center for the tribe. The Cuyapaipe Band focuses on preserving their traditions and language while also engaging in economic development initiatives to support their community.