Conformational isomers, also known as conformers, are different spatial arrangements of the same molecule that result from rotation around single bonds. These variations do not involve breaking any bonds, allowing the molecule to adopt various shapes while maintaining its connectivity. The most common example of conformational isomers can be seen in alkanes, where the rotation around the carbon-carbon bonds leads to distinct conformations, such as staggered and eclipsed forms. The energy differences between these conformations can influence the stability and reactivity of the molecule, making conformational isomerism an important concept in organic chemistry.