The Commerce Clause is a provision in the United States Constitution, specifically found in Article I, Section 8. It grants Congress the power to regulate commerce among the states, with foreign nations, and with Native American tribes. This clause has been fundamental in allowing the federal government to manage economic activities and ensure a unified national market. Over the years, the Commerce Clause has been interpreted broadly by the courts, enabling Congress to pass laws affecting various aspects of economic life, such as labor relations and environmental regulations. Landmark cases, like Wickard v. Filburn, have expanded its reach, demonstrating its significance in shaping federal authority over interstate commerce.