Cofilin is a protein that plays a crucial role in the regulation of the cytoskeleton, which is the structural framework of cells. It primarily binds to actin, a protein that forms filaments and is essential for various cellular functions, including movement and shape. By severing and depolymerizing actin filaments, Cofilin helps to control the dynamics of the cytoskeleton, allowing cells to adapt to their environment. Cofilin is involved in several cellular processes, such as cell migration, division, and response to signals. Its activity is tightly regulated, as improper function can lead to issues like cancer progression or neurodegenerative diseases. Understanding Cofilin's role can provide insights into these conditions and potential therapeutic approaches.