Cmin refers to the minimum concentration of a drug in the bloodstream after it has been administered and before the next dose is given. It is an important pharmacokinetic parameter that helps determine the effectiveness and safety of a medication. Maintaining an appropriate Cmin ensures that the drug remains effective without causing toxicity. In clinical settings, Cmin is used to guide dosing regimens for various medications, especially antibiotics and chemotherapy agents. By monitoring Cmin, healthcare providers can adjust dosages to achieve optimal therapeutic levels, ensuring that patients receive the best possible treatment outcomes while minimizing side effects.