The City of Destruction is a fictional location from the allegorical novel The Pilgrim's Progress by John Bunyan. It represents a place filled with sin and moral decay, where inhabitants are unaware of their spiritual peril. The city symbolizes the worldly distractions and temptations that lead people away from salvation. In the story, the protagonist, Christian, leaves the City of Destruction in search of Celestial City, a representation of heaven. His journey highlights the importance of recognizing one's spiritual state and the need for redemption. The city serves as a cautionary backdrop for those seeking a more meaningful life.