"Cheech and Chong's Up in Smoke" is a 1978 comedy film directed by Lou Adler. It follows the misadventures of two stoners, Cheech Marin and Tommy Chong, as they embark on a road trip to Los Angeles. The film is known for its humorous portrayal of cannabis culture and the carefree lifestyle of its main characters. The plot centers around Cheech and Chong's attempts to create a band while inadvertently getting involved in a series of comedic situations. The film became a cult classic and is often credited with popularizing the stoner film genre, influencing many movies that followed.