Caspase-8 is an enzyme that plays a crucial role in the process of programmed cell death, known as apoptosis. It is part of a family of proteins called caspases, which are responsible for executing the death program in cells. Caspase-8 is typically activated in response to signals from death receptors on the cell surface, leading to a cascade of events that ultimately result in cell death. In addition to its role in apoptosis, Caspase-8 is also involved in inflammation and immune responses. It can activate other caspases and proteins that help regulate these processes, making it an important player in maintaining cellular health and responding to stress or damage. Understanding Caspase-8 is essential for research into various diseases, including cancer and autoimmune disorders.