C-Type Lectin Receptors (CLRs) are a group of proteins found on the surface of certain immune cells. They play a crucial role in recognizing and binding to specific carbohydrates, particularly those found on pathogens like bacteria and fungi. This binding helps the immune system identify and respond to infections. CLRs are important for initiating immune responses and can influence inflammation and tissue repair. They are involved in various processes, including the activation of dendritic cells and macrophages, which are key players in the body's defense against disease. Understanding CLRs can aid in developing new therapies for infections and autoimmune disorders.