Brule County is located in the state of South Dakota, in the United States. It was established in 1883 and is named after the Brule Sioux, a Native American tribe. The county seat is Chamberlain, which is situated along the Missouri River. The county covers an area of approximately 1,200 square miles and has a population of around 5,000 residents. Brule County is known for its agricultural activities, with farming and ranching being significant contributors to the local economy. The region also offers recreational opportunities, including fishing and boating on the Missouri River.