In "The Legend of Zelda: Breath of the Wild," the main antagonists are the four Divine Beasts and their corrupted forms, known as the Blights. Each Blight represents a different element and is tied to a specific region of Hyrule. Players must defeat these powerful foes to free the Divine Spirits and restore balance to the land. Another significant antagonist is Calamity Ganon, the dark force threatening Hyrule. He is the ultimate evil that has taken over Hyrule Castle and seeks to destroy Link and Princess Zelda. Players must confront Ganon in an epic battle to save Hyrule and its inhabitants.