A "breakthrough" refers to a significant and sudden advance in knowledge, technology, or understanding that leads to new possibilities. These moments often occur after extensive research and experimentation, resulting in discoveries that can change the course of a field. For example, the development of the internet revolutionized communication and information sharing worldwide. Breakthroughs can happen in various areas, including science, medicine, and engineering. In medicine, a breakthrough might involve a new treatment or vaccine, such as the rapid development of COVID-19 vaccines. Such advancements can improve lives and address pressing global challenges, showcasing the power of innovation.