Beta-lactamase inhibitors are compounds that help combat bacterial resistance to beta-lactam antibiotics, such as penicillins and cephalosporins. Bacteria produce beta-lactamase enzymes that break down these antibiotics, rendering them ineffective. By inhibiting these enzymes, the inhibitors allow the antibiotics to work effectively against resistant bacterial strains. Common examples of beta-lactamase inhibitors include clavulanic acid, sulbactam, and tazobactam. These substances are often combined with beta-lactam antibiotics to enhance their effectiveness. This combination therapy is crucial in treating infections caused by resistant bacteria, improving patient outcomes in various clinical settings.