Bcl-xL
Bcl-xL is a protein that plays a crucial role in regulating cell survival and apoptosis, which is the process of programmed cell death. It belongs to the Bcl-2 family of proteins, known for their functions in controlling cell death and promoting cell survival. By inhibiting apoptosis, Bcl-xL helps cells resist stress and can contribute to the development of certain diseases, including cancer.
In addition to its role in cancer, Bcl-xL is also involved in various physiological processes, such as immune response and tissue homeostasis. Its expression is tightly regulated, and dysregulation can lead to pathological conditions. Understanding Bcl-xL's functions is important for developing targeted therapies in diseases where cell survival is a key factor.