Barstow is a city located in San Bernardino County, California. It is situated in the Mojave Desert and serves as a key transportation hub, connecting major highways like Interstate 15 and Interstate 40. The city has a rich history, particularly as a stop for travelers during the California Gold Rush and the Old West. Today, Barstow is known for its proximity to several attractions, including the Mojave National Preserve and Calico Ghost Town. The city also hosts the Barstow Route 66 Museum, which celebrates the famous highway's history and significance in American culture.