B.E.16, or "B.E. 16," refers to a specific year in the Buddhist Era, which is used in several Southeast Asian countries. The Buddhist calendar is based on the life of the Buddha, with the year 543 BCE considered the starting point. Therefore, B.E.16 corresponds to 528 CE in the Gregorian calendar. In countries like Thailand and Cambodia, the Buddhist Era is commonly used alongside the Gregorian calendar for official and cultural purposes. B.E.16 is significant in the context of historical events and cultural practices that occurred during that time, reflecting the influence of Buddhism in the region.