Azure CLI is a command-line tool that allows users to manage and configure resources in the Microsoft Azure cloud platform. It provides a set of commands that can be executed in a terminal or command prompt, making it easier to automate tasks and manage cloud services without needing a graphical user interface. With Azure CLI, users can create, update, and delete resources such as virtual machines, databases, and storage accounts. It supports various operating systems, including Windows, macOS, and Linux, and can be integrated into scripts for more complex automation tasks, enhancing productivity and efficiency in cloud management.