Aquaporin-3 is a type of protein that forms channels in cell membranes, allowing water and small molecules to pass through. It is part of the aquaporin family, which plays a crucial role in regulating water balance in various tissues. Aquaporin-3 is particularly important in the kidneys, skin, and eyes, where it helps maintain hydration and supports various physiological processes. This protein is encoded by the AQP3 gene and is found in many organisms, including humans. Aquaporin-3 also facilitates the transport of glycerol, which is important for energy metabolism and cell signaling. Its proper function is essential for maintaining cellular homeostasis and overall health.