The Appleton, Wisconsin Metropolitan Statistical Area (MSA) includes the city of Appleton and surrounding communities in Outagamie, Calumet, and Winnebago counties. This region is part of the larger Fox River Valley and is known for its diverse economy, which includes manufacturing, healthcare, and education. The Appleton MSA has a population of approximately 225,000 residents, making it one of the larger metropolitan areas in Wisconsin. The area features various recreational opportunities, cultural attractions, and educational institutions, contributing to a vibrant community atmosphere.