"Appleseed" is a science fiction manga series created by Masamune Shirow. It is set in a post-apocalyptic future where society is rebuilding after a devastating war. The story follows Deunan Knute, a skilled soldier, and her partner Briareos Hecatonchires, a cyborg, as they navigate the challenges of a new world and the complexities of human and artificial life. The narrative explores themes of technology, politics, and the nature of humanity. It is known for its detailed artwork and philosophical undertones, making it a significant work in the cyberpunk genre. The series has also inspired several animated adaptations and video games.