Amazing Fantasy #15, published in August 1962, is a landmark comic book that introduced the iconic character Spider-Man. Created by writer Stan Lee and artist Steve Ditko, this issue tells the origin story of a young man named Peter Parker, who gains superpowers after being bitten by a radioactive spider. The comic explores themes of responsibility and the consequences of power, encapsulated in the famous phrase, "With great power, there must also come great responsibility." Amazing Fantasy #15 is celebrated for its innovative storytelling and character development, marking the beginning of a new era in superhero comics.