Alpha-1, or Alpha-1 Antitrypsin Deficiency, is a genetic condition that affects the production of a protein called alpha-1 antitrypsin. This protein is crucial for protecting the lungs and liver from damage caused by enzymes. When the body does not produce enough of this protein, it can lead to serious health issues, including lung diseases like emphysema and liver problems such as cirrhosis. Diagnosis of Alpha-1 typically involves blood tests to measure the levels of alpha-1 antitrypsin in the body. Treatment options may include lifestyle changes, medications, and in some cases, alpha-1 antitrypsin replacement therapy. Early detection and management are essential for improving quality of life for those affected.