Alpha 1, or Alpha-1 Antitrypsin Deficiency, is a genetic condition that affects the production of a protein called alpha-1 antitrypsin (AAT). This protein is crucial for protecting the lungs and liver from damage caused by enzymes. When AAT levels are low, individuals may experience lung diseases, such as emphysema, and liver problems, including cirrhosis. The condition is inherited in an autosomal co-dominant manner, meaning that both copies of the gene contribute to the overall level of AAT in the body. Diagnosis typically involves blood tests to measure AAT levels, and treatment may include lifestyle changes, medications, or in severe cases, liver transplantation.