Adeno-Associated Virus
Adeno-Associated Virus (AAV) is a small virus that belongs to the family of parvoviruses. It is known for its ability to infect humans and other primates without causing disease. AAV is often used in gene therapy because it can deliver genetic material into cells effectively, making it a valuable tool for treating genetic disorders.
AAV requires a helper virus, such as adenovirus or herpesvirus, to replicate. It has a simple structure, consisting of a single-stranded DNA genome surrounded by a protein coat. Researchers are exploring its potential in various medical applications, including treatments for conditions like hemophilia and muscular dystrophy.