ADCC
ADCC, or Antibody-Dependent Cellular Cytotoxicity, is an immune response mechanism where antibodies bind to target cells, marking them for destruction. This process involves immune cells, particularly natural killer (NK) cells, which recognize and kill the antibody-coated cells. ADCC plays a crucial role in the body's defense against infections and cancer.
In therapeutic contexts, ADCC is leveraged in monoclonal antibody treatments, where engineered antibodies are designed to enhance this immune response against specific diseases. By promoting ADCC, these treatments can effectively target and eliminate harmful cells, making them a vital tool in modern medicine, especially in oncology.